Hi Welcome to healhcaremagic After going through your query I concluded that your wife have osteoarthritis of the both knees. I give such patients coming to my clinic Diacerine and glucosamine with good results . Analgesic such as ibuprofen for pain relief is useful. Vitamin D3 supplements can be used if its level is low. Quadriceps exercises are helpful. You can discuss your doctor about it. Hope your query get answered. If you have any clarification then please don t hesitate to write to us. I will be happy to answer your queries. You can also write to me directly on below link: https://www.bit.ly/askdrsudhirortho Wishing you good health. Take care.