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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Underwent Lumpectomy. Prescribed Tamoxifen For Life. Lifelong Medication Necessary?

I had a lumpectomy and axilliary clearance 11-3/4 years ago for Grade 1 Invasing Duct Carcinoma with the lump being described as moderately differentiated infiltrating duct carcinoma (NOS) Grade 1. It was both estrogen and progesterone posive. I underwent radiation treatment then commenced Tamoxifen 20mg. I was on the 20mg for 10 years, and my surgeon (who I see every 12 months) advised that he would drop me back to a 'maintenance' dose of 10 mg, and wants me to stay on it for life. Most people I know are only on 20mg for 5 years then stop taking Tamoxifen. What are your thoughts?
Mon, 4 Nov 2013
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OBGYN,  's  Response
Hello
Thanks for your query.
The subject you have raised is one that is under intense research and debate.
As a standard of practice, Tamoxifen is definitely continued at the very least for 5 years.
Newer consensus is emerging that continuing it for longer periods than even 5 years is now recommended and beneficial.
There is no scientific recommendation for taking it life long at least.
Since you have taken it already for 10 years, I dont see any need for taking it any longer.
wish you all the best.
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Underwent Lumpectomy. Prescribed Tamoxifen For Life. Lifelong Medication Necessary?

Hello Thanks for your query. The subject you have raised is one that is under intense research and debate. As a standard of practice, Tamoxifen is definitely continued at the very least for 5 years. Newer consensus is emerging that continuing it for longer periods than even 5 years is now recommended and beneficial. There is no scientific recommendation for taking it life long at least. Since you have taken it already for 10 years, I dont see any need for taking it any longer. wish you all the best.