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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Frequent Mouth Ulcers And Eye Irritation?

Am querying current line of thinking by several consultants. Admitted to hospital May 2011; lumbar puncture showed elevated CSF protein of 1088 mg/L with 228 white cells, 95% lymphocytes. The working diagnosis was viral meningitis, and I was discharged after 2 days aciclovir. Negative for herpes simplex virus 1 and 2. Developed infection in leg early October 2011, followed by painful groin, then ulcers either side of scrotum - non painful, and diagnosed as shingles. Mid October 2011, following tinitus, buzzing , hearing different frequencies, then vertigo, admitted for 2 weeks in ID ward...CSF showed 614 white cells with 90% lymphocytosis. CSF protein raised at 1335 mg/L. Tested for everything under the sun, incl. HIV, syphillis, Lyme disease, Cat scratch fever (leg infection thought to have been through an insect bite). All negative, incl. ANA. Chest x-ray, MRI scan of brain and whole spine also negative. Admitted again 26th December 2011, aciclovir for seven days, now back home feeling well, if a little tired. Current thought is Mollarets meningitis, but more recently, rheumatology dept. thinking Behcets syndrome, as I suffer from mouth ulcers. My contention is this; I have sufferd from mouth ulcers since a teenager taking exams at school. If I have a job interview, I will get mouth ulcers after @ 48 hours. Dentist thinks stress induced, as do I. I have no aching joints and no eye irritation, also, just found out that HLAB51 negative. I am a 42 year old British male and caucasian. I can t help feeling there s a square peg being pushed into a round hole here. What about migraine; the tinitus, buzzing and vertigo? Also, I took a non-steroidal (Ibuprofen) prior to the first two episodes. Bickerstaff s encephalitis sounds just as plausible as Behcets...or am I in denial? I would appreciate any advice, even if it s to simply face the music . Thank you for your time.
Mon, 2 Jul 2018
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Internal Medicine Specialist 's  Response
Hi,
Thank you for trusting HCM.
Dear, all the signs and symptoms you have described point out it as BEHCETS syndrome.
Behcets also causes meningitis and migraine type symptoms.
HLA B51 IS simply a genetic marker not a conclusive evidence that completely eliminate behcets possibility.

You can ask your doctor to do a PATHERGY TEST, for conclusive diagnosis. Along with skin biopsy, lumbar puncture.
Take care
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What Causes Frequent Mouth Ulcers And Eye Irritation?

Hi, Thank you for trusting HCM. Dear, all the signs and symptoms you have described point out it as BEHCETS syndrome. Behcets also causes meningitis and migraine type symptoms. HLA B51 IS simply a genetic marker not a conclusive evidence that completely eliminate behcets possibility. You can ask your doctor to do a PATHERGY TEST, for conclusive diagnosis. Along with skin biopsy, lumbar puncture. Take care