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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Numbness And Swelling In Hand After Having Nardil?

I ve begun taking an anti-depressant, Nardil, about 5 or 6 weeks ago. Barely any side effects. However, in the past few days (about a week after increasing the dose from 30mg to 45mg) I noticed that I wake up with my hands numb and swollen. I never had this problem before. Is this serious?
Mon, 2 May 2022
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General & Family Physician,  's  Response
Hi,

Nardil contains phenelzine that belongs to the group of antidepressant medications known as monoamine oxidase inhibitors or MAOIs is used in the treatment of depression, panic attacks etc. Just like other medication, this medication has some side effects of its own. Again, sometimes increasing the dose of this medication may initiate or aggravate some side effects.

It may cause tingling or numbness of the hands or feet, swollen hands, legs or ankles, trembling or shaking of the hands or feet, dizziness, drowsiness, tiredness, weakness, sleeping disturbances, constipation, dry mouth, changes in appetite, weight gain, allergic reactions and many more. Usually most of these side effects are mild as well as self limiting and go away over time as the body adjusts to this medication. In case these side effects persist for long, then you should consult your doctor immediately for medical help.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Zubayer Alam, General And Family Physician
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What Causes Numbness And Swelling In Hand After Having Nardil?

Hi, Nardil contains phenelzine that belongs to the group of antidepressant medications known as monoamine oxidase inhibitors or MAOIs is used in the treatment of depression, panic attacks etc. Just like other medication, this medication has some side effects of its own. Again, sometimes increasing the dose of this medication may initiate or aggravate some side effects. It may cause tingling or numbness of the hands or feet, swollen hands, legs or ankles, trembling or shaking of the hands or feet, dizziness, drowsiness, tiredness, weakness, sleeping disturbances, constipation, dry mouth, changes in appetite, weight gain, allergic reactions and many more. Usually most of these side effects are mild as well as self limiting and go away over time as the body adjusts to this medication. In case these side effects persist for long, then you should consult your doctor immediately for medical help. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Zubayer Alam, General And Family Physician