Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties
159 Doctors Online

By proceeding, I accept the Terms and Conditions

Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

HCM Blog Instant Access to Doctors
HCM BlogQuestions Answered
HCM Blog Satisfaction

What Does The Following Biopsy Report Mean?

I recently had a biopsy performed and this was the result on my lab:"Vacuolar Interface Dermatitis. The histological differential diagnosis includes a connective tissue disorder such as subacute or SLE or dermatomyositis. The histologic features of lupus profundus are not present. The differential diagnosis can be expanded to include lichen striatus in view of clinical history of linearly arranged papules. Clinical and/or serologic correlation is recommended. Sections show vascular alteration and necrotic keratinocytes along the dermal-epidermal junction and superficial predominantly lymphocytic infiltrates. Sections demonstrate subtle mucin deposition within the dermis."I am currently being watched by a rheumatologist for the possibility of Lupus or Behçet's...could this help in the diagnosis either way? Is there a simple English explanation for the biopsy findings?
Fri, 14 Nov 2014
Report Abuse
Pulmonologist 's  Response
Thanks for your quetion on HCM.
Vacuolar interface dermatitis can be seen in SLE (lupus) and dermatomyocitis.
Both are connective tissue disease.
Better to get done full ANA profile. If antids DNAand antism antibodies are present than chances of SLE are more.
And if they are absent chances of dermatomyocitis are more.
More over clinical features like small joint pain, butterfly rash on face etc are favouring SLE more.
So I think you should discuss about full ANA profile with your rheumatologist.
I find this answer helpful

 1 user finds this helpful

Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer. For a more detailed, immediate answer, try our premium service [Sample answer]
Share on
 

Related questions you may be interested in


Recent questions on Biopsy


Loading Online Doctors....
What Does The Following Biopsy Report Mean?

Thanks for your quetion on HCM. Vacuolar interface dermatitis can be seen in SLE (lupus) and dermatomyocitis. Both are connective tissue disease. Better to get done full ANA profile. If antids DNAand antism antibodies are present than chances of SLE are more. And if they are absent chances of dermatomyocitis are more. More over clinical features like small joint pain, butterfly rash on face etc are favouring SLE more. So I think you should discuss about full ANA profile with your rheumatologist.