Hello, Thanks for posting. I think the cause of the joint effusion should be investigated first. Septic arthritis and gout could be responsible so some lab test should be done to exclude those. If no specific cause is found, then the pain should be managed as arthrosis. Pain management is multidisciplinary include physical therapy and use of pain killers (antiinflammatory/analgesia). Oral pain killers could be started and the dosage and class should be increased gradually till optimal dosages are reached. If pain not still managed despite physical therapy and pain killers. Other options like steroids orally or injected directly into the knee joints can be used. Counselling is very essential to also manage your psychological state as the pain; despite the fact that fluid was found in your knee joints, could still be aggravated by your psychological state. Maintaining exercise is recommended in also managing the pain and stopping completely can also cause the pain to become worst. Treating the underlying cause is also important. You can pay a visit to a rheumatologist. Hope this helps