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what are the causes of hypoalbuminemia and generalized edema in a neonate? a 20 day old with unremarkable antenatal history presented with facial puffiness and both limbs edema, pitting in nature since birth.serum albumin was 1.8.on ultrasound, minimal ascites was present.
after 2 months edema resolved itself without any treatment.
HI THANKS FOR YOUR QUERY. IN THIS CASE THE LOW PROTEIN COULD BE EXCLUSIVELY DUE TO "MINIMAL CHANGE DISEASE/NEPHROTIC SYNDROME."THE CLINICALLY HISTORY GOES COMPLETELY IN FAVOUR OF THIS. THIS DISEASE RESULTS BECAUSE OF THE IMMATURE RENAL SYSTEM ASSOCIATED WITH LEAKY MEMBRANES LEADING TO GROSS LOSS OF PROTEIN IN THE URINE LEADING TO HYPOALBUMINEMIA. OTHER CAUSES WOULD BE PROTEIN LOOSING GUT DISORDERS AND MALNUTRITION.THE DEFINITIVE TREATMENT WOULD BE ADMINISTRATION OF STEROIDS AND IMMUNOSUPPRESENTS .THE DISORDER IS STRICTLY BENIGN AND SHOWS EXCELLENT RESPONSE TO THE ABOVE TREATMENT.THANK YOU
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What Causes Of Hypoalbuminemia?
HI THANKS FOR YOUR QUERY. IN THIS CASE THE LOW PROTEIN COULD BE EXCLUSIVELY DUE TO MINIMAL CHANGE DISEASE/NEPHROTIC SYNDROME. THE CLINICALLY HISTORY GOES COMPLETELY IN FAVOUR OF THIS. THIS DISEASE RESULTS BECAUSE OF THE IMMATURE RENAL SYSTEM ASSOCIATED WITH LEAKY MEMBRANES LEADING TO GROSS LOSS OF PROTEIN IN THE URINE LEADING TO HYPOALBUMINEMIA. OTHER CAUSES WOULD BE PROTEIN LOOSING GUT DISORDERS AND MALNUTRITION.THE DEFINITIVE TREATMENT WOULD BE ADMINISTRATION OF STEROIDS AND IMMUNOSUPPRESENTS .THE DISORDER IS STRICTLY BENIGN AND SHOWS EXCELLENT RESPONSE TO THE ABOVE TREATMENT.THANK YOU