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Malignant melanoma arises from melanocytes in a pigmented area (eg, skin, mucous membranes, eyes, or CNS). With spread, prognosis is poor. Melanomas occur mainly on the skin but also on the mucosa of the oral and genital regions and conjunctiva. Melanomas vary in size, shape, and color (usually pigmented) and in their propensity to invade and metastasize.

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Stasis Dermatitis- skin inflamation

Stasis dermatitis is inflammation of the skin of the lower legs caused by chronic venous insufficiency.Stasis dermatitis occurs in patients with chronic venous insufficiency because blood pools in the legs, causing persistent edema.

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Hives

Urticaria is migratory, erythematous, pruritic plaques. Urticaria is classified as acute (< 6 wk) or chronic (> 6 wk). The term angioedema refers to deep dermal or subcutaneous swellings. Isolated angioedema without wheals may be due to deficiency of C1 esterase inhibitor.

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Pemphigus Vulgaris

Pemphigus vulgaris is an uncommon, potentially fatal, autoimmune disease characterized by intraepidermal blisters and extensive erosions on apparently healthy skin and mucous membranes such as mouth or on your genitals.

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Bullous pemphigoid

Bullous pemphigoid is an autoimmune skin disorder producing chronic, pruritic bullous eruptions in elderly patients. Usually on the arms, legs or trunk. Without treatment, bullous pemphigoid may persist, with periods of remission and flare-ups, for many years.

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Contact Dermatitis

Contact dermatitis is acute inflammation of the skin caused by irritants or allergens. The primary symptom is pruritus; skin changes range from erythema to blistering and ulceration, often on or near the hands but occurring on any exposed skin surface.

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Dermatophytoses

Dermatophytoses are fungal infections of keratin in the skin and nails, frequently affects hair also. Human infections are caused by Epidermophyton, Microsporum, and Trichophyton spp. Transmission is person-to-person, animal-to-person, and rarely, soil-to-person. The organism may persist indefinitely. Most people do not develop clinical infection; HIV and diabetes are common risk factors.

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Ichthyosis

Ichthyosis is a skin disorder that causes dead skin cells to accumulate in thick, dry scales on the skin's surface. These scales can be present at birth, but usually first appear in early childhood. Sometimes Ichthyosis vulgaris disappears entirely for most of the adult years, only to return later. Ichthyosis can also be a sign of systemic disease.

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Exfoliative Dermatitis

Exfoliative dermatitis is widespread erythema and scaling of the skin caused by preexisting skin disease like (eg, atopic dermatitis, contact dermatitis, seborrheic dermatitis, and psoriasis), certain drugs, and malignancy (leukemia, adenocarcinoma)

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Squamous cell carcinoma

Squamous cell carcinoma is the second most common form of nonmelanoma skin cancer following basal cell carcinoma. Squamous cell carcinomas are usually slow growing and can be difficult to spot, especially when they appear on skin that has other signs of sun damage, such as changes in pigmentation, loss of elasticity and wrinkling.

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