Pure red cell aplasia (PRCA) describes a condition in which RBC precursors in bone marrow are nearly absent, while megakaryocytes and WBC precursors are usually present at normal levels. Pure red cell aplasia exists in several forms, and the most common form is an acute self-limited condition. Congenital pure red cell aplasia is a lifelong disorder, and it is associated with physical abnormalities. Acquired pure red cell aplasia is often chronic and is associated with underlying disorders such as thymomas and autoimmune diseases.

It is the carrier protein for growth hormone. It is coded by the gene which codes growth hormone receptor.It is decreased in genetic hormone insensitivity (Laron syndrome).

Amyotrophic Lateral Sclerosis (ALS) is a form of motor neuron disease which is progressive, fatal, neurodegenerative disease caused by the degeneration of motor neurons, the nerve cells in the central nervous system that control voluntary muscle movement resulting in progressive muscle wasting and atrophy.

A peptic ulcer is a sore area or erosion on the lining of the digestive system. If it is in the stomach it is called as gastric ulcer, if it is in the duodenum it is called duodenal ulcer.

Yunis Varon syndrome is a rare and congenital disorder which involves multiple system malfunctions of the body. It generally affects the skeletal system, ectodermal system and sometimes the cardiorespiratory system is also suffered with various malfunctions.