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It refers to the association of three rare disorders. These disorders are congenital occurring at birth. They involve malformations of eyes, ears, and spine. It is also known as Golden-Gorlin syndrome, OAVS

Impetigo is a contagious skin infection which produces blisters or sores on the face, neck, hands and diaper area. It is the most common skin infections seen in children.

Idiopathic Peripheral Periphlebitis also called Eales Disease is a rare disease of eye characterized by sudden loss of vision, due to inflammation of the blood vessels of the eye leading to recurrent hemorrhage into the eyeball as well as oozing of clear thick fluid from inside of the eyeball.

Bleeding during or after intercourse, often termed post-coital bleeding, can occur because of many reasons. Cervical cancer is one of the most serious causes of post-coital bleeding. However, it is not the only cause. In fact, less than 6 percent women presenting with post-coital bleeding are likely to be diagnosed with invasive cancer. Some of the more common causes of bleeding associated with intercourse are precancerous changes in the cervix, cervical ectropion, infections and inflammation. Whatever the cause of bleeding associated with intercourse, it is not a symptom that you should ignore. It is advisable to contact your doctor at the earliest if you are experiencing bleeding during or after intercourse.

It is a very rare disorder causing severe bleeding. Factor X111 or fibrin stabilizing factor is an enzyme of the blood coagulation system.